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BIT’s progress in design and preparation of single-atom nanozymes

News Resource: School of Materials

Editor: News Agency of BIT

Translator: Guo Yating, News Agency of BIT

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Picture 1 Preparation strategy of High-Performance Single-atom Nanozymes

Beijing Institute of Technology, November 18th, 2021: On November 2, Journal of the American Chemical Society published a research article titled “Thermal Atomization of Platinum Nanoparticles into Single Atoms: An Effective Strategy for Engineering High-Performance Nanozymes”.

Nanozymes become an ideal alternative to natural enzymes with their high stability, low cost and easy storage. However, the current catalytic performance of nanozymes cannot meet their applications in fields such as biomedicine. With the rapid development of nanoscience and technology, the emerging single-atom nanozymes take a single metal atom as the active center and show excellent performance in various catalytic reactions. However, due to the lack of stable bonding effect between the mental active center and the carrier of the currently prepared single-atom nanozymes, as well as the high specific surface free energy, individual metal atoms have a strong tendency to migrate and gather into particles, which directly leads to the catalytic performance degradation or even inactivation of single-atom nanozymes. This paper establishes a universal method for preparing highly active and covalently stable metal monoatomic nanozymes, which can directly pyrolyze platinum metal nanoparticles from nanoscale to single atomic platinum and stabilizes the metal active center through the coordination bonding of N, P and S. This process increases the peroxidase-like catalytic efficiency of individual platinum active centers from 9960 M-1s-2 to more than 1 million. The research work opens up new ideas for the rational design and optimization of artificial enzyme simulation enzymes.

The corresponding authors of the article are Professor Liang Minmin of School of Materials of Beijing Institute of Technology (BIT) and Professor Wang Dingsheng of Tsinghua University. This study has been supported by National Key R & D Projects, Chinese National Natural Science Foundation and the Youth Innovation Promotion Association of the Chinese Academy of Sciences.

Paper Information: Yuanjun Chen, Peixia Wang, Haigang Hao, Juanji Hong, Haijing Li, Shufang Ji, Ang Li, Rui,Gao, Juncai Dong, Xiaodong Han, Minmin,Liang*, Dingsheng Wang*, Yadong Li. Thermal Atomization of Platinum Nanoparticles into Single Atoms: An Effective Strategy for Engineering High-Performance Nanozymes. J. Am. Chem. Soc. (2021) https://doi.org/10.1021/jacs. 1c08581

Paper link: https://pubs.acs.org/doi/abs/10.1021/jacs.1c08581